Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, fever, and inflammation. It is often prescribed alongside Lipitor, a medication used to lower cholesterol levels in the blood. While there is no evidence to suggest that ibuprofen worsens the side effects of Lipitor, it is important to be aware of the potential side effects of both medications.

Lipitor is known to cause gastrointestinal side effects, such as nausea, diarrhea, and indigestion [2]. In some cases, these side effects can be severe enough to cause gastroesophageal reflux disease (GERD), a condition in which stomach acid flows back into the esophagus, causing heartburn and other symptoms [2]. If you experience these symptoms while taking Lipitor, it is important to talk to your doctor about adjusting your dosage or switching to a different medication.

Excessive sweating is not a common side effect of either ibuprofen or Lipitor [3]. However, it is listed as a possible side effect of some medications, so it is important to be aware of this potential side effect if you are taking multiple medications [3]. If you experience excessive sweating while taking ibuprofen or Lipitor, it is important to talk to your doctor to determine the cause and whether any adjustments to your medication regimen are necessary.

In conclusion, while there is no evidence to suggest that ibuprofen worsens the side effects of Lipitor, it is important to be aware of the potential side effects of both medications. If you experience any symptoms while taking these medications, it is important to talk to your doctor to determine the cause and whether any adjustments to your medication regimen are necessary.

Sources:
[1] Drug Patent Watch. "Ibuprofen Trademark Details." Accessed August 16, 2021. https://www.drugpatentwatch.com/p/tradename/IBUPROFEN.
[2] Mayo Clinic. "Heartburn/GERD." Accessed August 16, 2021. https://www.mayoclinic.org/diseases-conditions/gerd/expert-answers/heartburn-gerd/faq-20058535.
[3] GoodRx. "Medications That Can Cause Excessive Sweating as a Side Effect." Accessed August 16, 2021. https://www.goodrx.com/drugs/side-effects/medications-cause-excessive-sweating-side-effect.