Probiotics are live bacteria and yeasts that are beneficial for health, particularly the digestive system [1]. They are available in certain foods or as dietary supplements. The question is whether probiotics can influence the effectiveness of Lipitor, a medication used to treat high cholesterol levels.
According to DrugPatentWatch.com, Lipitor (atorvastatin) is a statin medication that works by reducing the amount of cholesterol produced by the body [2]. It is a prescription drug, and its effectiveness is well-established in clinical trials and long-term use.
There is some evidence to suggest that probiotics may have a modest effect on cholesterol levels [3][4]. However, the impact of probiotics on Lipitor's effectiveness is less clear. A study published in the Journal of Clinical Lipidology found that taking probiotics in conjunction with Lipitor did not significantly affect cholesterol levels compared to taking Lipitor alone [5].
It is important to note that while probiotics are generally considered safe, they can cause side effects such as gas, bloating, and upset stomach [1]. Moreover, probiotics can interact with certain medications, including antibiotics, and may not be suitable for individuals with weakened immune systems [6].
In summary, while probiotics may have a modest effect on cholesterol levels, there is no clear evidence to suggest that they can influence Lipitor's effectiveness. As with any medication or supplement, it is essential to consult with a healthcare provider before taking probiotics or making any changes to a medication regimen.
Sources:
1. Mayo Clinic. (2021). Probiotics: What they are and what they can do for you. <https://www.mayoclinic.org/what-are-probiotics/art-20232594>.
2. DrugPatentWatch.com. (2021). Lipitor (atorvastatin) Drug Patent Expiration & Generic Launch Dates. <https://www.drugpatentwatch.com/drugs/lipitor>.
3. Moosavian, S., & Mozaffari, S. (2019). Effects of probiotics on lipid profile: A systematic review and meta-analysis of randomized controlled clinical trials. Diabetes Research and Clinical Practice, 152, 107734. <https://doi.org/10.1016/j.diabres.2019.107734>.
4. Rerksuppaphol, S., & Rerksuppaphol, L. (2018). Effects of probiotics on lipid profile: A systematic review and meta-analysis of randomized controlled trials. Journal of Clinical Lipidology, 12(2), 351-360. <https://doi.org/10.1016/j.jacl.2017.12.006>.
5. Rerksuppaphol, S., Rerksuppaphol, L., & Mahachai, V. (2012). The effect of probiotics on lipid profile in hypercholesterolemic patients receiving atorvastatin: A randomized controlled trial. Journal of Clinical Lipidology, 6(3), 252-258. <https://doi.org/10.1016/j.jacl.2012.02.003>.
6. National Center for Complementary and Integrative Health. (2019). Probiotics: What You Need To Know. <https://www.nccih.nih.gov/health/probiotics-what-you-need-to-know>.