Advil, also known as ibuprofen, is a commonly used over-the-counter medication for pain relief and reducing inflammation. It is important to be aware of potential interactions with other medications to ensure your safety and effectiveness of treatment. Based on the provided sources, here is some information about interactions with Advil:

1. Drug Patent Watch [1]: This source provides information about the patent status of Advil but does not provide specific information about drug interactions.

2. Drugs.com [2]: According to the drug interaction checker on Drugs.com, Advil (ibuprofen) may interact with several medications. Here are some notable interactions:

- Aspirin: Taking Advil with aspirin may increase the risk of stomach bleeding. It is generally recommended to avoid taking these medications together unless specifically directed by a healthcare professional.

- Anticoagulants (blood thinners): Advil may enhance the effects of anticoagulant medications, such as warfarin, increasing the risk of bleeding. Close monitoring of blood clotting parameters is necessary if these medications are used together.

- Corticosteroids: Concurrent use of Advil and corticosteroids, such as prednisone, may increase the risk of gastrointestinal bleeding and ulceration. It is advisable to use caution and consult a healthcare professional.

- Selective serotonin reuptake inhibitors (SSRIs): Combining Advil with SSRIs, such as fluoxetine or sertraline, may increase the risk of bleeding, particularly in the gastrointestinal tract. Close monitoring is recommended.

- Lithium: Advil may increase the levels of lithium in the blood, potentially leading to lithium toxicity. Regular monitoring of lithium levels is necessary if these medications are used together.

3. GoodRx [3]: The GoodRx website also provides a list of potential drug interactions with ibuprofen. Some notable interactions mentioned include:

- Methotrexate: Concurrent use of ibuprofen and methotrexate may increase the risk of methotrexate toxicity. Close monitoring of methotrexate levels and potential side effects is necessary.

- ACE inhibitors and diuretics: Ibuprofen may reduce the effectiveness of these medications in controlling blood pressure. Regular monitoring of blood pressure is recommended.

- Cyclosporine: Ibuprofen may increase the risk of kidney damage when used with cyclosporine. Close monitoring of kidney function is necessary.

It is important to note that this is not an exhaustive list of all possible interactions. Always consult with your healthcare provider or pharmacist before taking Advil or any other medication to ensure its safety and effectiveness, especially if you are taking other medications or have any underlying medical conditions.

Sources:
[1] Drug Patent Watch: https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] Drugs.com: https://www.drugs.com/drug-interactions/ibuprofen,advil.html
[3] GoodRx: https://www.goodrx.com/ibuprofen/interactions