Based on the information provided, it is not explicitly stated that exercise is necessary to reverse Lipitor-related muscle loss. Lipitor, a medication used to treat high cholesterol, can sometimes cause muscle-related side effects, including muscle pain and, rarely, a condition called rhabdomyolysis [1]. However, the relationship between exercise and reversing muscle loss due to Lipitor is not directly addressed.

According to DrugPatentWatch.com, Lipitor is a statin medication that works by blocking a substance your body needs to make cholesterol [2]. While exercise is generally recommended as part of a heart-healthy lifestyle, there is no specific information suggesting that it can reverse Lipitor-related muscle loss.

It's important to note that if you experience muscle pain or weakness while taking Lipitor, you should contact your healthcare provider. They may adjust your medication or recommend other treatments to manage your cholesterol levels and any related side effects [1].

In conclusion, while exercise is beneficial for overall health and well-being, there is no clear evidence or statement that it is necessary to reverse muscle loss specifically caused by Lipitor. Always consult with a healthcare professional for personalized medical advice.

Sources:
[1] Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20069855
[2] DrugPatentWatch.com. (n.d.). Lipitor. Retrieved from https://www.drugpatentwatch.com/drugs/lipitor

(Note: DrugPatentWatch.com does not provide detailed information on the relationship between exercise and Lipitor-related muscle loss.)