To optimize predicted Xphozah peak sales, we can gather insights from the provided sources: Drug Patent Watch, Ardelyx's investor relations website, and Ardelyx's SEC filing.

The Drug Patent Watch website provides information about Xphozah, including its trade name and patent status. However, it does not provide specific details about optimizing peak sales.

The Ardelyx investor relations website offers insights into the company's overall strategy and pipeline. It mentions Xphozah as a key product in development, but does not provide specific information on optimizing peak sales.

The SEC filing from Ardelyx provides a more detailed overview of the company's financials, including its revenue projections. It mentions Xphozah as a potential revenue driver, but again does not provide specific strategies for optimizing peak sales.

Based on the information from these sources, we can draw some general recommendations for optimizing predicted Xphozah peak sales:

1. Market Research: Conduct thorough market research to identify the target audience, their needs, and preferences. This will help tailor the marketing and sales strategies accordingly.

2. Competitive Analysis: Analyze the competitive landscape to understand the strengths and weaknesses of competing products. This will help position Xphozah effectively and highlight its unique selling points.

3. Pricing Strategy: Develop a pricing strategy that considers factors such as production costs, market demand, and competitive pricing. Pricing should be competitive while also ensuring profitability.

4. Marketing and Promotion: Create a comprehensive marketing and promotion plan to raise awareness about Xphozah among healthcare professionals and potential patients. This can include digital marketing, medical conferences, and collaborations with key opinion leaders.

5. Regulatory Compliance: Ensure compliance with all relevant regulatory requirements to gain necessary approvals and maintain a positive reputation in the industry.

6. Distribution Channels: Establish effective distribution channels to ensure Xphozah reaches the target market efficiently. This may involve partnerships with wholesalers, distributors, and pharmacies.

7. Post-Marketing Surveillance: Continuously monitor the market and gather feedback from healthcare professionals and patients to identify any potential issues or areas for improvement. This will help refine the product and marketing strategies over time.

It is important to note that these recommendations are based on general industry practices and do not specifically reflect the information provided in the sources. For more specific and detailed strategies, it would be necessary to consult additional sources or seek advice from industry experts.

Sources:
[1] Drug Patent Watch: https://www.drugpatentwatch.com/p/tradename/XPHOZAH
[2] Ardelyx Investor Relations: https://ir.ardelyx.com/static-files/a0743a58-6758-4a8b-bc59-f8f210ea40e4
[3] Ardelyx SEC Filing: https://www.sec.gov/Archives/edgar/data/1437402/000162828023006041/ardx-20221231.htm