Lipitor is a brand name for atorvastatin, which is a medication that belongs to the statin class of drugs. Statins are primarily used to lower cholesterol levels and reduce the risk of cardiovascular events such as heart attacks and strokes. However, the effect of Lipitor on blood pressure levels is less clear.
According to DrugPatentWatch [1], Lipitor does not have a direct effect on blood pressure levels. However, it can indirectly impact blood pressure by reducing the risk of cardiovascular events. High blood pressure is a risk factor for cardiovascular disease, and reducing the risk of these events can help to lower blood pressure levels.
While Lipitor is generally well-tolerated, it can cause some side effects, as noted by Medical News Today [2]. These can include muscle pain, weakness, and tenderness, as well as gastrointestinal symptoms such as nausea, diarrhea, and constipation. In rare cases, Lipitor can also cause more serious side effects such as liver damage and rhabdomyolysis, a condition in which muscle fibers break down and release their contents into the bloodstream.
A study conducted by Pfizer [3] found that adding Lipitor to effective blood pressure treatment provided a significant reduction in heart attacks or deaths from heart attacks over five years. The study involved over 10,000 patients with high blood pressure and at least one other cardiovascular risk factor. The patients were randomly assigned to receive either Lipitor or a placebo in addition to their blood pressure medication. The results showed that the group receiving Lipitor had a 36% reduction in the risk of heart attack or death from heart attack compared to the placebo group.
In conclusion, while Lipitor does not have a direct effect on blood pressure levels, it can indirectly impact blood pressure by reducing the risk of cardiovascular events. However, it is important to note that Lipitor can cause side effects, and patients should discuss the risks and benefits of the medication with their healthcare provider.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.medicalnewstoday.com/articles/drugs-lipitor-side-effects
[3] https://www.pfizer.com/news/press-release/press-release-detail/adding_lipitor_early_to_effective_blood_pressure_treatment_provided_a_significant_reduction_in_heart_attacks_or_deaths_from_heart_attacks_over_five_years