Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. According to Drug Patent Watch [1], there are no known drug interactions between Lipitor and antidepressants. However, it is important to note that certain antidepressants can increase the risk of developing muscle-related side effects when taken with Lipitor.

A study published in the National Library of Medicine [2] found that selective serotonin reuptake inhibitors (SSRIs), a class of antidepressants, can increase the risk of developing muscle-related side effects when taken with Lipitor. The study suggests that patients taking both medications should be closely monitored for muscle pain, weakness, and tenderness.

Another source, GoodRx [3], lists the potential interaction between Lipitor and Paxlovid, an antiviral medication used to treat COVID-19. According to the website, taking Lipitor with Paxlovid can increase the risk of muscle-related side effects, and patients should be monitored closely.

In conclusion, while there are no known drug interactions between Lipitor and antidepressants, certain antidepressants, specifically SSRIs, can increase the risk of developing muscle-related side effects when taken with Lipitor. Patients taking both medications should be closely monitored for any potential side effects. Additionally, taking Lipitor with Paxlovid can also increase the risk of muscle-related side effects, and patients should be monitored closely.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827898/
[3] https://www.goodrx.com/paxlovid/drug-interactions