Aspirin, also known as acetylsalicylic acid, is a commonly used medication for pain relief, fever reduction, and blood thinning. However, it is important to be aware of the potential risks associated with taking too much aspirin, as it can lead to an overdose. The sources you provided, including Drug Patent Watch [1], Mount Sinai Health Library [2], and Healthline [3], offer valuable information on aspirin overdose.

An aspirin overdose occurs when an individual takes more than the recommended dosage, which can result in various symptoms and potentially life-threatening complications. The exact amount of aspirin that constitutes an overdose can vary depending on several factors, including an individual's age, weight, overall health, and any underlying medical conditions they may have [2].

According to the sources, a toxic dose of aspirin is generally considered to be greater than 150 mg per kilogram of body weight. This means that for an average adult weighing 70 kilograms (154 pounds), a toxic dose would be approximately 10,500 mg or 10.5 grams [2][3]. However, it is important to note that even lower doses can be harmful, especially for children or individuals with certain health conditions [3].

When an overdose occurs, it can lead to symptoms such as ringing in the ears (tinnitus), dizziness, confusion, rapid breathing, nausea, vomiting, and abdominal pain. In severe cases, an overdose can cause more serious complications, including internal bleeding, organ damage, seizures, and even coma [2][3].

If you suspect an aspirin overdose, it is crucial to seek immediate medical attention. Healthcare professionals can provide appropriate treatment to help prevent further complications. Treatment may include measures to remove the excess aspirin from the body, such as activated charcoal or gastric lavage, as well as supportive care to manage symptoms and monitor vital signs [2].

To prevent an aspirin overdose, it is essential to follow the recommended dosage instructions provided by healthcare professionals or indicated on the packaging. If you have any concerns or questions about aspirin use, it is always advisable to consult with a healthcare provider [3].

In conclusion, an aspirin overdose can occur when an individual takes more than the recommended dosage. The toxic dose of aspirin is generally considered to be greater than 150 mg per kilogram of body weight. However, even lower doses can be harmful, especially for children or individuals with certain health conditions. If an overdose is suspected, immediate medical attention should be sought to prevent further complications.

Sources:
[1] Drug Patent Watch: https://www.drugpatentwatch.com/p/tradename/ASPIRIN
[2] Mount Sinai Health Library: https://www.mountsinai.org/health-library/poison/aspirin-overdose
[3] Healthline: https://www.healthline.com/health/aspirin-overdose