Based on the available information, there can be potential side effects when combining Lipitor and wine. Lipitor, also known as atorvastatin, is a medication used to treat high cholesterol and prevent heart disease [1]. When consuming alcohol, especially in excess, it can increase the levels of triglycerides, a type of fat, in the blood [2]. High levels of triglycerides can increase the risk of heart disease [2].

According to Verywell Health, "moderate alcohol consumption" is generally not harmful when taking Lipitor [2]. However, it is important to note that "moderate" consumption is typically defined as up to one drink per day for women and up to two drinks per day for men [2]. Consuming more than this amount can increase the risk of negative interactions between Lipitor and alcohol [2].

The Recovery Village states that "drinking alcohol while taking Lipitor can increase the risk of liver damage" [3]. This is because both Lipitor and alcohol are metabolized by the liver [3]. Excessive alcohol consumption can already put a strain on the liver, and adding Lipitor to the mix can further increase this strain [3].

In summary, while moderate alcohol consumption may not be harmful when taking Lipitor, consuming excessive amounts of alcohol can increase the risk of negative interactions between Lipitor and alcohol, including an increased risk of liver damage and high triglyceride levels [2][3]. It is always best to consult with a healthcare provider before mixing any medication with alcohol.

Sources:
[1] <https://www.drugpatentwatch.com/p/tradename/LIPITOR>
[2] <https://www.verywellhealth.com/can-i-drink-wine-if-i-take-lipitor-1124044>
[3] <https://www.therecoveryvillage.com/alcohol-abuse/alcohol-and-lipitor/>