Acyclovir is an antiviral medication that is used to treat infections caused by herpes viruses. According to the sources provided, there are no known interactions between acyclovir and antidepressants. However, it is always important to consult with a healthcare professional before taking any medication, especially if you are taking other medications or have any underlying medical conditions.

The first source, Drug Patent Watch [1], provides information on the patent status of acyclovir. It does not provide any information on the safety of taking acyclovir with antidepressants.

The second source, Drugs.com [2], provides a list of potential drug interactions with acyclovir. Antidepressants are not listed as a drug that interacts with acyclovir. However, the website recommends consulting with a healthcare professional before taking any medication, especially if you are taking other medications.

The third source, WebMD [3], provides detailed information on acyclovir, including its uses, side effects, and precautions. The website does not mention any interactions between acyclovir and antidepressants.

In conclusion, based on the sources provided, there are no known interactions between acyclovir and antidepressants. However, it is important to consult with a healthcare professional before taking any medication, especially if you are taking other medications or have any underlying medical conditions.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ACYCLOVIR
[2] https://www.drugs.com/drug-interactions/acyclovir.html
[3] https://www.webmd.com/drugs/2/drug-941/acyclovir-oral/details