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What happens if you mix lipitor and grapefruit?



Lipitor is a brand name for the drug atorvastatin, which is used to lower cholesterol levels in the body [1]. Grapefruit contains a compound called furanocoumarin, which can interfere with the body's ability to break down certain medications, including atorvastatin [2]. This interference can cause the medication to build up in the body to potentially dangerous levels, increasing the risk of side effects [3].

According to GoodRx, it is recommended that individuals taking atorvastatin avoid consuming grapefruit or grapefruit juice [2]. The interaction between atorvastatin and grapefruit can lead to an increased risk of side effects, such as muscle pain, weakness, and kidney damage [2]. Additionally, the interaction can increase the risk of rhabdomyolysis, a rare but serious condition in which muscle tissue breaks down and releases a protein into the bloodstream that can damage the kidneys [2].

RO Health also advises against consuming grapefruit or grapefruit juice while taking atorvastatin [3]. They recommend speaking with a healthcare provider if you have any concerns about the interaction between atorvastatin and grapefruit.

In conclusion, consuming grapefruit or grapefruit juice while taking atorvastatin can interfere with the body's ability to break down the medication, potentially leading to an increased risk of side effects and other complications. It is recommended that individuals taking atorvastatin avoid consuming grapefruit or grapefruit juice [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.goodrx.com/classes/statins/why-cant-i-have-grapefruit-with-my-statin
[3] https://ro.co/health-guide/lipitor-and-grapefruit/



Follow-up:   Can lipitor and grapefruit cause side effects? How does grapefruit affect lipitor absorption? Is it safe to eat grapefruit while taking lipitor?





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