Flolan is a medication used to treat pulmonary arterial hypertension (PAH). If you are considering discontinuing Flolan, it is important to speak with your healthcare provider first. They will provide you with a plan to gradually reduce your dose to avoid any adverse effects.

According to the prescribing information [2], Flolan should not be stopped abruptly, as it may cause rebound pulmonary hypertension, which can be life-threatening. Therefore, the dosage should be gradually decreased over a period of three to four days. The recommended method is to decrease the dose by 2 ng/kg/min every 2 to 4 hours until the infusion is stopped.

It is essential to monitor patients closely during this process to ensure that they do not experience any adverse effects. The healthcare provider should monitor the patient's blood pressure, heart rate, and symptoms of pulmonary hypertension.

In conclusion, if you are considering discontinuing Flolan, you should speak with your healthcare provider. They will provide you with a plan to gradually reduce your dose over a period of three to four days to avoid any adverse effects. It is essential to monitor patients closely during this process to ensure that they do not experience any adverse effects.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/FLOLAN
[2] https://gskpro.com/content/dam/global/hcpportal/en_US/Prescribing_Information/Flolan/pdf/FLOLAN-PI-PIL.PDF
[3] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=8e4b636e-ee9c-4111-779d-28c8369d283b.