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How does lipitor interact with grapefruit juice?



Lipitor is a brand name for the drug atorvastatin, which belongs to a class of drugs called statins. Statins are used to lower cholesterol levels in the blood. Grapefruit juice is known to interact with many drugs, including statins like Lipitor.

Grapefruit juice contains compounds that inhibit an enzyme in the liver responsible for breaking down certain drugs, including Lipitor. When this enzyme is inhibited, the drug can build up in the body to potentially dangerous levels, increasing the risk of side effects. This interaction can occur even if the grapefruit juice is consumed hours before or after taking the medication.

Therefore, it is recommended that patients taking Lipitor avoid consuming grapefruit juice or any other grapefruit products. This includes whole grapefruit, grapefruit segments, and grapefruit extract. Patients should also consult their healthcare provider before consuming any other citrus fruits or juices.

In conclusion, patients taking Lipitor should avoid consuming grapefruit juice or any other grapefruit products to prevent potentially dangerous interactions. It is important to consult a healthcare provider before making any changes to medication or diet.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.goodrx.com/classes/statins/why-cant-i-have-grapefruit-with-my-statin
[3] https://www.verywellhealth.com/can-i-take-lipitor-or-zocor-with-grapefruit-juice-1124045



Follow-up:   What are the risks of combining Lipitor and grapefruit juice? Can Lipitor dosage be adjusted when consuming grapefruit juice? Are there any other foods that interact with Lipitor?





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