Based on the information provided, I was unable to find specific data on how often Lipitor alters protein creation. However, Lipitor, also known as Atorvastatin, is a statin medication that works by blocking a substance your body needs to make cholesterol [1]. By inhibiting the HMG-CoA reductase enzyme, Lipitor reduces the production of mevalonate, a key intermediate in the cholesterol biosynthesis pathway [2].

Although there is no direct evidence on the frequency of protein creation alteration, Lipitor's primary mechanism of action impacts the mevalonate pathway, which is involved in the biosynthesis of various proteins, sterols, and isoprenoids [3]. Consequently, Lipitor may indirectly affect the production of certain proteins.

For a more comprehensive understanding of how often specific drugs like Lipitor alter protein creation, consulting resources such as DrugPatentWatch.com [4] or other scientific literature may provide further insights.

Sources:
[1] Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/description/drg-20063056
[2] PubChem. (2021). Atorvastatin. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Atorvastatin
[3] National Center for Biotechnology Information. (2021). Mevalonate pathway. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK535421/
[4] DrugPatentWatch. (n.d.). Lipitor (Atorvastatin) Drug Patent Expiration, Sales & Prescribing Data. Retrieved from https://www.drugpatentwatch.com/lipitor-atorvastatin-drug-patent-expiration-sales-prescribing-data/