Ozempic (generic name: semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist, which is used to improve glycemic control in adults with type 2 diabetes. GLP-1 receptor agonists work by mimicking the functions of natural hormones in your body to control blood sugar levels [1].
In addition to its blood sugar-lowering effects, Ozempic has been shown to have an impact on appetite regulation and weight loss. This is achieved through several mechanisms, including slowing gastric emptying, which leads to a prolonged feeling of fullness [2].
A study published in the journal Diabetes, Obesity and Metabolism found that participants who took Ozempic experienced a greater reduction in hunger and an increase in feelings of fullness compared to those who took a placebo [3]. This effect on appetite regulation may be due to the drug's impact on the areas of the brain that control appetite and food intake [4].
It is important to note that while Ozempic may help to reduce hunger and increase feelings of fullness, it should not be used as a sole method for weight loss. It is typically prescribed as an adjunct to diet and exercise for the management of type 2 diabetes [5].
In summary, Ozempic can change your sensation of fullness prior to eating by slowing gastric emptying and affecting the areas of the brain that control appetite and food intake, leading to a reduction in hunger and an increase in feelings of fullness.
Sources:
1. <https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/ Ozempic-semaglutide-injection>
2. <https://www.ncbi.nlm.nih.gov/books/NBK538223/>
3. <https://onlinelibrary.wiley.com/doi/full/10.1111/dom.13403>
4. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876132/>
5. <https://www.drugpatentwatch.com/drugs/ozempic>