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Which liver conditions specifically restrict lipitor use?



After reviewing the provided sources, I found that Lipitor (atorvastatin) use is generally not recommended for individuals with certain liver conditions.

According to the Mayo Clinic, statins like Lipitor can cause an increase in liver enzymes, which can be a sign of liver damage [${2}]. However, it's important to note that actual liver damage due to statin use is rare. Still, due to this potential risk, Lipitor is not recommended for people with liver diseases or abnormal liver function tests [${2}].

The drug's FDA-approved label also states that Lipitor is contraindicated in patients with active liver disease or unexplained persistent elevations in serum transaminases [${1}].

Furthermore, DrugWatch mentions that Lipitor can cause liver enzyme abnormalities and, in rare cases, liver failure [${3}].

In summary, Lipitor use is not recommended for individuals with active liver disease, unexplained persistent elevations in serum transaminases, or abnormal liver function tests.

Sources:
[1] <https://www.drugpatentwatch.com/p/tradename/LIPITOR>
[2] <https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013>
[3] <https://www.drugwatch.com/lipitor/side-effects/>



Follow-up:   Which specific liver diseases limit Lipitor use? Can Lipitor be taken with liver disease? Are there liver ailments incompatible with Lipitor?





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