Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood [1]. Joint supplements, on the other hand, are used to improve joint health and reduce inflammation [2].

According to the Mayo Clinic, some of the common side effects of Lipitor include muscle pain, tenderness, and weakness [2]. It is important to note that these side effects can be exacerbated by taking certain supplements, such as red yeast rice and St. John's wort, which can also affect the liver and interact with Lipitor [2]. However, there is no specific information on joint supplements interacting negatively with Lipitor.

One supplement that should be avoided while taking Lipitor is grapefruit. Grapefruit can interfere with the liver's ability to metabolize Lipitor, which can lead to higher levels of the medication in the bloodstream and an increased risk of side effects [3].

In conclusion, while there is no specific information on negative interactions between joint supplements and Lipitor, it is important to be cautious when taking any supplements while on medication. It is always best to consult with a healthcare provider before starting any new supplements or medications to ensure there are no potential negative interactions.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013
[3] https://www.healthline.com/health/high-cholesterol/grapefruit-and-statins