Lipitor is a brand name for the drug atorvastatin, which is used to lower cholesterol levels in the blood. According to the sources provided, there is no direct interaction between Lipitor and over-the-counter (OTC) painkillers. However, it is important to note that some painkillers, such as nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and aspirin, can increase the risk of muscle damage when taken with statins like Lipitor [3].

Additionally, it is important to be aware of potential drug interactions when taking Lipitor with other medications. For example, the antiviral drug ritonavir, which is used to treat HIV and COVID-19, can increase the levels of Lipitor in the blood and increase the risk of side effects [2].

It is always recommended to consult with a healthcare provider or pharmacist before taking any new medications, including OTC painkillers, while taking Lipitor. They can provide guidance on potential drug interactions and help ensure that the medications are safe to take together.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.covid19treatmentguidelines.nih.gov/therapies/antivirals-including-antibody-products/ritonavir-boosted-nirmatrelvir--paxlovid-/paxlovid-drug-drug-interactions/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334287/