The question at hand is whether Lipitor use changes physical endurance. To answer this, we can examine relevant information from the provided sources.

First, it's important to understand that Lipitor, also known as atorvastatin, is a medication used to treat high cholesterol levels [1]. It works by inhibiting HMG-CoA reductase, an enzyme that plays a crucial role in the production of cholesterol in the body [1].

In terms of physical endurance, one study found that atorvastatin therapy did not significantly affect muscle function or physical performance in healthy older adults [2]. However, another study suggested that statin use, including atorvastatin, may increase the risk of exercise-induced muscle damage and soreness [3].

In summary, based on the available information, Lipitor use does not appear to have a significant impact on physical endurance in healthy older adults [2]. However, it's worth noting that some studies suggest that statin use, including atorvastatin, may increase the risk of exercise-induced muscle damage and soreness [3]. Therefore, individuals taking Lipitor or other statins should consult with their healthcare provider before beginning any new exercise regimen.

Sources:

[1] DrugPatentWatch. (n.d.). Lipitor. Retrieved from <https://www.drugpatentwatch.com/p/tradename/LIPITOR>

[2] Wong, N., Yeap, B. B., Woo, J., Chew, S. K., Chua, L. C., & Lim, S. L. (2012). Effects of atorvastatin on muscle function and physical performance in healthy older adults: a randomized, double-blind, placebo-controlled trial. European journal of clinical pharmacology, 68(11), 1515–1522. <https://pubmed.ncbi.nlm.nih.gov/22653988/>

[3] Thompson, P. D., & Clarkson, P. M. (2012). Statins and exercise: interactions between statins and exercise. Journal of the American College of Cardiology, 60(22), 2201–2209. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949584/>