Muscle pain is a possible side effect of both Lipitor and ACE inhibitors, but its prevalence varies depending on the drug and the individual. Lipitor, also known as atorvastatin, is a cholesterol-lowering medication that can cause muscle pain in some people. According to Drug Patent Watch [1], muscle pain is listed as a common side effect of Lipitor, occurring in 1-10% of patients. However, the actual incidence of muscle pain may be higher, as some studies have reported rates as high as 20% [1]. It is important to note that severe muscle pain or weakness, along with dark urine or yellowing of the skin or eyes, can be signs of a rare but serious side effect called rhabdomyolysis [1]. If these symptoms occur, medical attention should be sought immediately.

ACE inhibitors, which are commonly used to treat high blood pressure, can also cause muscle pain in some people. According to the Mayo Clinic [2], muscle pain is a possible side effect of ACE inhibitors, but it is rare. The incidence of muscle pain with ACE inhibitors is not specified, but the Mayo Clinic notes that it is more common in people who are also taking a statin medication, such as Lipitor [2].

In addition to muscle pain, both Lipitor and ACE inhibitors can cause other side effects. For example, ACE inhibitors can cause a persistent dry cough [2], while Lipitor is listed by AARP [3] as a medication that can cause insomnia. As with any medication, it is important to discuss the potential risks and benefits with a healthcare provider before starting treatment.

Sources:

[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/ace-inhibitors/art-20047480
[3] https://www.aarp.org/health/drugs-supplements/info-04-2013/medications-that-can-cause-insomnia.html