Advil is a brand name for ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, fever, and inflammation. While Advil is generally considered safe when taken as directed, there are some potential side effects to be aware of.

One of the main concerns with taking Advil before bed is the risk of gastrointestinal (GI) side effects. NSAIDs like ibuprofen can irritate the lining of the stomach and intestines, potentially leading to stomach ulcers, bleeding, or perforation [2]. These risks are increased in people who take NSAIDs regularly, at high doses, or for long periods of time [2]. To minimize the risk of GI side effects, it's recommended to take Advil with food or milk, and to avoid taking it for extended periods of time without consulting a healthcare provider [2].

Another potential side effect of taking Advil before bed is drowsiness or dizziness. While these side effects are not common, they can occur in some people, especially if they take higher doses of Advil or if they are sensitive to the medication [1]. If you experience drowsiness or dizziness after taking Advil, it's important to avoid driving or operating heavy machinery until the effects wear off [1].

Finally, there is some evidence to suggest that taking NSAIDs like Advil before bed may disrupt sleep quality. A study published in the journal Sleep Medicine found that taking ibuprofen before bed led to decreased sleep quality and increased wakefulness during the night [3]. However, more research is needed to confirm these findings and to determine whether they apply to other NSAIDs or to people with different sleep patterns [3].

In conclusion, while Advil is generally safe when taken as directed, there are some potential side effects to be aware of when taking it before bed. These include GI side effects, drowsiness or dizziness, and possible disruptions to sleep quality. If you have any concerns about taking Advil before bed or if you experience any side effects, it's important to talk to your healthcare provider.

Sources:
[1] DrugPatentWatch. Advil. Retrieved from https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] Cleveland Clinic. Is It Bad to Take Ibuprofen Every Day? Retrieved from https://health.clevelandclinic.org/is-it-bad-to-take-ibuprofen-every-day/
[3] Lichstein, K. L., Griffin, K. L., Stone, K. C., & Riedel, B. W. (2006). Changes in sleep after bedtime administration of ibuprofen. Sleep Medicine, 7(3), 218-222. doi: 10.1016/j.sleep.2005.09.006