Lipitor is a medication that is used to lower cholesterol levels in the body. It contains atorvastatin, which is a statin drug that works by reducing the production of cholesterol in the liver [1]. According to the sources provided, it is generally safe to take Lipitor with supplements, but caution should be exercised when combining certain supplements with this medication.

ConsumerLab.com [2] suggests that certain supplements can interact with statins, including Lipitor. For example, taking large doses of niacin (vitamin B3) with statins can increase the risk of muscle damage. Additionally, taking supplements that contain red yeast rice can also increase the risk of muscle damage and liver toxicity. Therefore, it is recommended to speak with a healthcare provider before taking any supplements while on Lipitor.

The NHS [3] also advises caution when taking Lipitor with certain supplements. For example, taking St. John's Wort can reduce the effectiveness of Lipitor and increase the risk of side effects. Additionally, taking supplements that contain omega-3 fatty acids can also increase the risk of bleeding when taken with Lipitor. Therefore, it is important to inform a healthcare provider of any supplements being taken while on Lipitor.

In conclusion, while it is generally safe to take Lipitor with supplements, certain supplements can interact with this medication and increase the risk of side effects. Therefore, it is recommended to speak with a healthcare provider before taking any supplements while on Lipitor [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.consumerlab.com/answers/which-drugs-should-be-avoided-when-taking-statins/statin-supplement-interactions/
[3] https://www.nhs.uk/medicines/atorvastatin/taking-atorvastatin-with-other-medicines-and-herbal-supplements/