Yes, taking Lipitor (atorvastatin) and herbal supplements can potentially cause side effects. Lipitor is a statin medication used to treat high cholesterol and reduce the risk of stroke and heart attack [1]. Like all medications, Lipitor can have side effects, and combining it with herbal supplements may increase the risk or change the way the drug interacts with the body [2].

Herbal supplements can interact with Lipitor by affecting the drug's metabolism, absorption, or distribution in the body [3]. For example, St. John's Wort, a popular herbal supplement, can decrease the effectiveness of Lipitor by increasing its metabolism [4]. Grapefruit juice is another substance that can interact with Lipitor and increase the risk of side effects [5].

Common side effects of Lipitor include muscle pain, liver damage, and digestive problems [1]. When combined with herbal supplements, these side effects may become more severe or new side effects may occur. It is essential to consult a healthcare provider before taking any herbal supplements while on Lipitor [2].

In summary, taking Lipitor and herbal supplements can cause side effects, and it is crucial to consult a healthcare provider before combining the two.

Sources:

1. Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20069851?p=1>.
2. National Center for Complementary and Integrative Health. (2018). Herbs and Dietary Supplements: What You Need to Know. Retrieved from <https://www.nccih.nih.gov/health/herbs-and-dietary-supplements-what-you-need-to-know>.
3. DrugPatentWatch. (n.d.). Atorvastatin. Retrieved from <https://www.drugpatentwatch.com/drugs/atorvastatin>.
4. National Library of Medicine. (2021). St. John's Wort. Retrieved from <https://medlineplus.gov/druginfo/natural/952.html>.
5. National Library of Medicine. (2021). Grapefruit Juice and Some Drugs Don't Mix. Retrieved from <https://medlineplus.gov/grapefruitjuice.html>.