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Lipitor affect on muscle growth?



Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the body. It belongs to a class of drugs called statins, which work by inhibiting the enzyme HMG-CoA reductase, responsible for cholesterol synthesis in the liver.

There is some evidence that statins, including Lipitor, may affect muscle growth and function. A study published in the Journal of Cachexia, Sarcopenia and Muscle [2] found that statin use was associated with a decrease in muscle mass and strength in older adults. The study also found that statin use may exacerbate the effects of aging on muscle tissue. However, it is important to note that this study was conducted on a small sample size and further research is needed to confirm these findings.

Another study conducted by researchers at the Max Delbrück Center for Molecular Medicine in Berlin [3] found that statins may interfere with the production of a protein called mitofusin-2, which is essential for muscle cell fusion and growth. The study also found that statin use may lead to the accumulation of damaged mitochondria in muscle cells, which can contribute to muscle weakness and fatigue.

Despite these findings, Lipitor is generally considered safe and effective for the treatment of high cholesterol. However, it is important to discuss any concerns about muscle growth or function with a healthcare provider. They can provide guidance on the risks and benefits of Lipitor and recommend alternative treatments if necessary.

Sources:
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463373/
[3] https://www.mdc-berlin.de/news/press/what-statins-do-muscles



Follow-up:   Does Lipitor hinder muscle growth? How does Lipitor impact muscle development? Can Lipitor inhibit muscle strength gains?





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