While grapefruit juice is known to interact with Lipitor, there are other juices that may also affect the medication. According to Drug Patent Watch [1], Lipitor's active ingredient, atorvastatin, is metabolized by the liver's cytochrome P450 enzyme system. This system is also responsible for metabolizing other drugs, including some juices.
The Health Harvard website [2] explains that pomegranate juice and Seville orange juice can also interfere with the same enzyme system as grapefruit juice. These juices contain compounds that inhibit the activity of the cytochrome P450 enzyme system, leading to higher levels of atorvastatin in the bloodstream. This can increase the risk of side effects associated with the medication.
The NHS [3] also mentions that apple juice may affect the absorption of some medications, but there is no clear evidence that it interacts with atorvastatin specifically.
It is important to note that while these juices may affect the metabolism of atorvastatin, not all individuals may experience the same effects. It is recommended to speak with a healthcare provider or pharmacist before consuming any new juices or making significant changes to one's diet while taking Lipitor or any other medication.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.health.harvard.edu/heart-health/grapefruit-juice-and-statins
[3] https://www.nhs.uk/common-health-questions/medicines/does-grapefruit-affect-my-medicine/