Advil is a brand name for ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce fever. According to Drug Patent Watch [1], ibuprofen has been used for over 50 years, and it is available in various forms, including tablets, capsules, and liquid gels. Advil Migraine is a specific formulation of ibuprofen that is marketed for the treatment of migraines [2].

While ibuprofen is generally safe when used as directed, it can cause side effects in some people. The most common side effects of ibuprofen include stomach pain, nausea, and heartburn [2]. In rare cases, ibuprofen can cause more serious side effects, such as stomach ulcers, bleeding, and kidney problems [2]. It is important to take ibuprofen as directed and not to exceed the recommended dose.

Additionally, overuse of ibuprofen can lead to medication-overuse headaches, also known as rebound headaches [3]. This occurs when a person takes medication for headaches too frequently, and the medication itself causes headaches. Symptoms of medication-overuse headaches include headaches that occur more frequently and become more severe over time, as well as other symptoms such as nausea and difficulty sleeping [3].

In conclusion, Advil (ibuprofen) is generally safe when used as directed, but it can cause side effects in some people. The most common side effects include stomach pain, nausea, and heartburn. Rarely, ibuprofen can cause more serious side effects such as stomach ulcers, bleeding, and kidney problems. Overuse of ibuprofen can also lead to medication-overuse headaches. It is important to take ibuprofen as directed and not to exceed the recommended dose.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.webmd.com/drugs/2/drug-20833/advil-migraine-oral/details
[3] https://www.mayoclinic.org/diseases-conditions/medication-overuse-headache/symptoms-causes/syc-20377083