Lipitor is a brand name for the drug atorvastatin, which belongs to a class of medications called statins. Statins are commonly used to lower cholesterol levels and reduce the risk of heart disease [1]. While statins are generally considered safe and effective, there have been concerns about their potential side effects on muscle mass.

According to a study published in the Journal of Clinical Endocrinology and Metabolism, statins such as atorvastatin can decrease muscle mass and increase fat mass in older adults [2]. The study found that participants who took statins had lower muscle strength and physical performance compared to those who did not take statins.

Another study conducted by researchers at the Max Delbrück Center for Molecular Medicine in Berlin found that statins can interfere with the production of energy in muscle cells, leading to muscle weakness and fatigue [3]. The study also found that statins can reduce the number of mitochondria in muscle cells, which are responsible for producing energy.

However, it is important to note that not all studies have found a significant decrease in muscle mass with statin use. A review of multiple studies published in the Journal of Clinical Lipidology concluded that there is no consistent evidence to suggest that statins cause muscle loss or decrease muscle mass [4].

In conclusion, while some studies have suggested that statins such as Lipitor may decrease muscle mass, the evidence is not consistent. It is important to discuss any concerns about statin use and potential side effects with a healthcare provider.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463373/
[3] https://www.mdc-berlin.de/news/press/what-statins-do-muscles
[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598029/