Lipitor is a medication used to lower cholesterol levels in the blood. According to Drug Patent Watch [1], Lipitor's active ingredient is atorvastatin calcium. It is important to note that combining Lipitor with natural supplements may lead to adverse effects.

Consumer Lab [2] explains that certain supplements, such as red yeast rice, may contain compounds that are similar to the active ingredient in Lipitor. Therefore, taking these supplements with Lipitor may increase the risk of side effects. Additionally, St. John's Wort may reduce the effectiveness of Lipitor and should be avoided.

The NHS [3] also warns against taking certain supplements with Lipitor. For example, grapefruit juice can increase the levels of atorvastatin in the blood, which may lead to an increased risk of side effects. Additionally, supplements containing niacin may increase the risk of muscle problems when taken with Lipitor.

In conclusion, it is important to exercise caution when combining Lipitor with natural supplements. Some supplements may interact with Lipitor and increase the risk of side effects. It is recommended to consult with a healthcare professional before taking any supplements while on Lipitor.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.consumerlab.com/answers/which-drugs-should-be-avoided-when-taking-statins/statin-supplement-interactions/
[3] https://www.nhs.uk/medicines/atorvastatin/taking-atorvastatin-with-other-medicines-and-herbal-supplements/