Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. According to Drug Patent Watch [1], Lipitor is a substrate of the cytochrome P450 3A4 (CYP3A4) enzyme, which is responsible for its metabolism. Grapefruit juice is known to inhibit CYP3A4, which can lead to increased levels of Lipitor in the bloodstream and potentially increase the risk of side effects [3]. However, there is no evidence to suggest that other citrus fruits have the same effect on Lipitor absorption. In fact, a study published in the Journal of Clinical Pharmacology [2] found that orange juice did not affect the pharmacokinetics of atorvastatin. Therefore, it is unlikely that other citrus fruits will affect the absorption of Lipitor, but patients should still consult their healthcare provider before consuming any new foods or beverages while taking Lipitor.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589309/
[3] https://www.fda.gov/consumers/consumer-updates/grapefruit-juice-and-some-drugs-dont-mix