Lipitor is a medication used to lower cholesterol levels in the body. Grapefruit juice is known to interact with Lipitor, which can affect its absorption in the body. According to a study published in the Canadian Medical Association Journal, grapefruit juice can increase the absorption of Lipitor by up to 83%, leading to an increased risk of side effects [1]. This is because grapefruit juice contains compounds that inhibit the enzymes responsible for breaking down Lipitor in the liver, resulting in higher concentrations of the drug in the bloodstream [2].

It is recommended that patients taking Lipitor avoid consuming grapefruit juice or any grapefruit-containing products to prevent potential interactions. Patients should also inform their healthcare provider if they have a history of grapefruit juice consumption, as this can affect the dosage of Lipitor prescribed [3].

In conclusion, grapefruit juice can affect the absorption of Lipitor in the body by inhibiting the enzymes responsible for breaking down the drug in the liver. Patients taking Lipitor should avoid consuming grapefruit juice or any grapefruit-containing products to prevent potential interactions and should inform their healthcare provider of any grapefruit juice consumption.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.health.harvard.edu/heart-health/grapefruit-juice-and-statins
[3] https://ro.co/health-guide/lipitor-and-grapefruit/