Lipitor is a medication that contains the active ingredient atorvastatin, which is commonly used to lower cholesterol levels in patients with high cholesterol or cardiovascular disease. The need to change Lipitor schedules can be attributed to several factors, including the patent expiration, proper use guidelines, and individual patient needs.

Firstly, the patent expiration of Lipitor has led to the availability of generic versions of the medication. According to DrugPatentWatch, the patent for Lipitor expired in 2011, allowing other pharmaceutical companies to produce generic versions of atorvastatin[1]. This increased availability of generic options may lead to changes in Lipitor schedules as patients may switch to generic versions due to cost considerations or other factors.

Secondly, the Mayo Clinic provides guidelines on the proper use of atorvastatin, which can influence schedule changes. It is important to follow the instructions provided by healthcare professionals and the medication label. The Mayo Clinic recommends taking atorvastatin at the same time each day to help maintain a consistent level of the medication in the body[2]. However, individual patient needs may vary, and healthcare professionals may make adjustments to the schedule based on factors such as the patient's response to the medication or other medications they may be taking.

Additionally, individual patient needs and circumstances can also contribute to changes in Lipitor schedules. The National Center for Biotechnology Information (NCBI) states that atorvastatin can be taken with or without food, and the dose may be adjusted based on the patient's response to treatment and the goal of therapy[3]. Patients may also experience side effects or interactions with other medications, which may require changes in the timing or dosage of Lipitor.

In conclusion, Lipitor schedules may need to be changed due to factors such as the availability of generic versions, proper use guidelines, and individual patient needs. It is important for patients to follow the instructions provided by healthcare professionals and consult with them if any adjustments to the schedule are necessary.

Sources:
[1] DrugPatentWatch. Lipitor. Retrieved from: https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] Mayo Clinic. Atorvastatin (Oral Route): Proper Use. Retrieved from: https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/proper-use/drg-20067003
[3] National Center for Biotechnology Information. Atorvastatin. Retrieved from: https://www.ncbi.nlm.nih.gov/books/NBK430779/