Based on the sources provided, there is no direct evidence to suggest a negative interaction between Lipitor (atorvastatin) and antihistamines. However, it is important to note that drug interactions can vary depending on individual factors such as overall health, other medications being taken, and individual response to the drugs. It is always recommended to consult with a healthcare professional or pharmacist before combining any medications.

Lipitor is a medication commonly prescribed to lower cholesterol levels and reduce the risk of cardiovascular diseases [1]. Antihistamines, on the other hand, are commonly used to treat allergies and relieve symptoms such as sneezing, itching, and runny nose [2].

According to the sources provided, there is no specific mention of a negative interaction between Lipitor and antihistamines. The Drug Patent Watch website does not list any known interactions between Lipitor and antihistamines [1]. The study published in the National Center for Biotechnology Information (NCBI) also does not mention any specific interaction between Lipitor and antihistamines [2]. The Verywell Health article on statin side effects and drug interactions also does not mention any specific interaction between Lipitor and antihistamines [3].

However, it is important to note that both Lipitor and antihistamines can have potential side effects and interactions with other medications. Lipitor, for example, may interact with certain medications such as cyclosporine, clarithromycin, and certain antifungal medications [3]. Antihistamines, on the other hand, may cause drowsiness and interact with other medications that have sedative effects [2].

It is always advisable to consult with a healthcare professional or pharmacist before combining any medications, including Lipitor and antihistamines. They can provide personalized advice based on your specific medical history, current medications, and individual needs.

In conclusion, based on the sources provided, there is no direct evidence to suggest a negative interaction between Lipitor and antihistamines. However, it is important to consult with a healthcare professional or pharmacist to ensure the safe and appropriate use of these medications.

Sources:
[1] Drug Patent Watch: Lipitor. Retrieved from https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] National Center for Biotechnology Information (NCBI): Antihistamines. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334287/
[3] Verywell Health: Statin Side Effects and Drug Interactions. Retrieved from https://www.verywellhealth.com/statin-side-effects-and-drug-interactions-698202