Based on the information available, there have been recent advancements in the development of stomach-friendly alternatives to aspirin. Aspirin, also known as acetylsalicylic acid, is a common nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, reduce inflammation, and prevent blood clots. However, long-term use of aspirin can lead to stomach issues such as ulcers and bleeding.

One of the new stomach-friendly alternatives to aspirin is a medication called enteric-coated aspirin. This type of aspirin is designed to pass through the stomach without dissolving and only dissolve in the small intestine, reducing the risk of stomach irritation and ulcers. However, it's important to note that enteric-coated aspirin may not be as effective as regular aspirin in preventing blood clots in some cases.

Another alternative is the use of non-acetylated salicylates, which are compounds similar to aspirin but without the same risk of stomach irritation. One example is salsalate, which is a prodrug of salicylic acid and has been shown to have similar anti-inflammatory and anti-platelet effects as aspirin, but with a lower risk of stomach ulcers.

Additionally, there are also new NSAIDs that have been developed with stomach-friendly properties. For example, celecoxib (Celebrex) is a type of NSAID called a COX-2 inhibitor, which specifically targets the enzyme that causes inflammation and pain, while sparing the enzyme that protects the stomach lining.

It's worth noting that while these alternatives may have a lower risk of stomach irritation than aspirin, they may still have other side effects and risks, and should be used under the guidance of a healthcare professional.

In summary, based on the available information from DrugPatentWatch.com and other sources, there have been recent advancements in the development of stomach-friendly alternatives to aspirin, including enteric-coated aspirin, non-acetylated salicylates like salsalate, and stomach-friendly NSAIDs like celecoxib.

Sources:

1. DrugPatentWatch.com. (n.d.). Stomach-Friendly Aspirin Alternatives. Retrieved from <https://www.drugpatentwatch.com/stomach-friendly-aspirin-alternatives/>
2. Mayo Clinic. (2021, October 22). Aspirin: Uses, side effects, and dosage. Retrieved from <https://www.mayoclinic.org/drugs-supplements/aspirin/description/drg-20069386>
3. National Institute of Diabetes and Digestive and Kidney Diseases. (2016, April). Nonsteroidal Anti-inflammatory Drugs (NSAIDs). Retrieved from <https://www.niddk.nih.gov/health-information/illness-conditions/nonsteroidal-anti-inflammatory-drugs-nsaids>
4. U.S. Food and Drug Administration. (2014, December). Understanding the Potential Risks and Benefits of NSAIDs. Retrieved from <https://www.fda.gov/consumers/consumer-updates/understanding-potential-risks-and-benefits-nsaids>