Lipitor, also known as Atorvastatin, is a medication used to lower cholesterol levels in the blood. According to the sources provided, there is no specific information about when the discomfort associated with Lipitor starts. However, it is important to note that one of the common side effects of taking Lipitor is muscle pain or discomfort, which can occur at any time during the course of treatment [2]. This discomfort may be mild or severe, and it may affect one or more muscles in the body. In some cases, the discomfort may be accompanied by weakness or tenderness in the affected muscles [2].

It is important to consult with a healthcare provider if you experience any discomfort or side effects while taking Lipitor. They can evaluate your symptoms and determine if any changes to your medication regimen are necessary. In addition, there are steps you can take to prevent or minimize muscle pain while taking Lipitor, such as engaging in regular exercise, maintaining a healthy diet, and avoiding excessive alcohol consumption [3].

In summary, while there is no specific information about when the discomfort associated with Lipitor starts, muscle pain or discomfort is a common side effect that can occur at any time during treatment. It is important to speak with a healthcare provider if you experience any discomfort or side effects while taking Lipitor, and to take steps to prevent or minimize muscle pain.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20067003
[3] https://www.goodrx.com/classes/statins/muscle-pain-statins-how-to-prevent-common-side-effect