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Lipitor dosage for platelet aggregation?

Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels and reduce the risk of heart disease [1]. While it is not primarily used to affect platelet aggregation, some studies have investigated its effects on platelet function.

A study published in the Journal of Thrombosis and Haemostasis found that atorvastatin at a dose of 80mg/day significantly reduced platelet aggregation in patients with coronary artery disease [2]. However, the study did not investigate the effects of lower doses of atorvastatin on platelet aggregation.

Another study published in the journal Circulation investigated the effects of atorvastatin on platelet aggregation in patients with acute coronary syndrome. The study found that atorvastatin at a dose of 80mg/day significantly reduced platelet aggregation compared to placebo [3].

It is important to note that these studies were not specifically investigating the optimal dosage of atorvastatin for platelet aggregation. Therefore, it is unclear what the optimal dosage would be for this specific effect.

In conclusion, while atorvastatin has been shown to reduce platelet aggregation in some studies, the optimal dosage for this effect is unclear. It is important to consult with a healthcare provider to determine the appropriate dosage of atorvastatin for an individual's specific medical needs.


Follow-up:   What is the recommended lipitor dosage? How does lipitor affect platelet aggregation? Are there any side effects of lipitor on platelet aggregation?

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