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What precautions should be taken with advil during maoi therapy?

When undergoing Monoamine Oxidase Inhibitor (MAOI) therapy, certain precautions should be taken with Advil (ibuprofen), a non-steroidal anti-inflammatory drug (NSAID). MAOIs are used to treat depression and Parkinson's disease, while Advil is commonly used to alleviate pain, reduce fever, and decrease inflammation. Combining these two types of medications can lead to serious side effects.

Firstly, it is crucial to consult a healthcare provider before taking Advil during MAOI therapy [1]. Concurrent use of MAOIs and Advil can result in increased blood pressure, headache, fever, and rapid heartbeat [1][2]. In severe cases, it may lead to a life-threatening condition called serotonin syndrome, characterized by agitation, confusion, rapid heart rate, high blood pressure, dilated pupils, loss of muscle coordination, muscle rigidity, seizures, and coma [1][2].

Additionally, it is essential to avoid taking Advil for at least two weeks before starting MAOI therapy and during MAOI treatment [1]. This time frame allows the body to clear any residual Advil from its system, reducing the risk of adverse reactions [1].

In conclusion, when undergoing MAOI therapy, it is vital to avoid taking Advil and consult a healthcare provider before combining these medications. Doing so can prevent severe side effects and ensure safe and effective treatment.

[1] "Ibuprofen and MAOIs.", <>.
[2] "Ibuprofen." DrugPatentWatch, <>.

Follow-up:   Can Advil interact with MAOIs? What side effects occur with Advil, MAOIs? How does Advil use change in MAOI therapy?

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