Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood. According to the sources provided, there is evidence to suggest that taking Lipitor at night may be more effective for some people.

One reason for this is that the body's natural production of cholesterol is highest at night, so taking Lipitor before bed can help to block the production of cholesterol more effectively [2]. Additionally, Lipitor has a half-life of around 14 hours, meaning that taking it at night can ensure that it remains in the body for a longer period of time, providing more consistent cholesterol-lowering effects [3].

However, it is important to note that not everyone may experience better results from taking Lipitor at night. The optimal time to take Lipitor may vary depending on factors such as individual metabolism, other medications being taken, and the severity of the individual's cholesterol levels [1].

Therefore, it is recommended that patients consult with their healthcare provider to determine the best time to take Lipitor based on their individual needs and medical history.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.drugs.com/medical-answers/does-lipitor-work-better-if-you-take-it-at-night-416127/
[3] https://www.healthline.com/health/high-cholesterol/why-should-you-take-statins-at-night