According to the sources provided, the optimal time to take Lipitor (atorvastatin) may vary depending on individual factors and the advice of your healthcare provider.

The first source, Drug Patent Watch, provides information about the patent status of Lipitor but does not specifically address the timing of administration.

The second source, the National Health Service (NHS) in the UK, recommends taking atorvastatin once daily, preferably in the evening. This is because the body produces more cholesterol at night, and taking the medication before bed may help to maximize its effectiveness. However, it is important to note that the NHS advises following the instructions given by your doctor or pharmacist.

The third source, Drugs.com, also suggests taking atorvastatin at night, as this is when the body produces more cholesterol. It states that taking the medication at bedtime may lead to better results in terms of cholesterol reduction.

It is important to consult with your healthcare provider or pharmacist for personalized advice on when to take Lipitor. They can take into account your specific medical condition, other medications you may be taking, and any potential interactions or side effects. They will be able to provide you with the most accurate and appropriate guidance.

In summary, while the NHS and Drugs.com suggest taking Lipitor at night to potentially optimize its effectiveness, it is crucial to consult with your healthcare provider for personalized advice.

Sources:
[1] Drug Patent Watch: https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] NHS: https://www.nhs.uk/medicines/atorvastatin/how-and-when-to-take-atorvastatin/
[3] Drugs.com: https://www.drugs.com/medical-answers/does-lipitor-work-better-if-you-take-it-at-night-416127/