Lipitor is a medication used to lower cholesterol levels in the blood. The optimal time to take Lipitor depends on individual preferences and lifestyle. According to the National Health Service (NHS) [3], Lipitor can be taken at any time of the day, with or without food. However, some studies suggest that taking Lipitor at night may be more effective. Drugs.com [2] states that taking Lipitor at night can help to lower the risk of heart attacks and strokes. This is because the body produces more cholesterol at night, and taking Lipitor before bed can help to block the production of cholesterol. Additionally, taking Lipitor at night can reduce the risk of side effects, such as muscle pain, as the medication is metabolized more slowly during sleep. However, it is important to consult a doctor or pharmacist before changing the time of day that Lipitor is taken. Drug Patent Watch [1] provides information on the patent status of Lipitor, but does not provide information on the optimal time to take the medication.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.drugs.com/medical-answers/does-lipitor-work-better-if-you-take-it-at-night-416127/
[3] https://www.nhs.uk/medicines/atorvastatin/how-and-when-to-take-atorvastatin/