Based on the available information, there is no specific data or studies that directly address the frequency of Lipitor side effects involving protein production.

Lipitor, also known as atorvastatin, is a medication used to treat high cholesterol and prevent heart disease [1]. Common side effects of Lipitor include headache, muscle and joint pain, and digestive issues such as diarrhea and constipation [2].

However, there is some research suggesting that statins, the class of drugs to which Lipitor belongs, may have an impact on protein production. A study published in the Journal of Clinical Investigation found that statins can affect the production of certain proteins in the liver, including those involved in cholesterol metabolism [3].

Additionally, a review article published in Circulation Research notes that statins have been shown to affect the production of proteins involved in muscle function and inflammation [4].

It's important to note that while these studies suggest that statins may have an impact on protein production, they do not provide information on the frequency of these effects or their specific relevance to Lipitor.

In summary, while there is some evidence to suggest that Lipitor and other statins may affect protein production, there is no information available on the frequency of these effects. If you have concerns about potential side effects of Lipitor or any medication, it's important to speak with your healthcare provider.

Sources:

[1] <https://www.drugpatentwatch.com/p/tradename/LIPITOR>

[2] <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949584/>

[3] <https://www.jci.org/articles/view/37988>

[4] <https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.118.312782>