Lipitor and Crestor are both prescription drugs that are used to treat high cholesterol levels in the body. They are both classified as statins and work by reducing the amount of cholesterol produced by the liver. While they have similar mechanisms of action, there are some differences between the two drugs that may make one more suitable for certain individuals.

Lipitor, also known as atorvastatin, was approved by the FDA in 1996 and has been widely prescribed since then. It is available in both brand-name and generic forms and is typically taken once a day. Lipitor has been shown to be effective in reducing LDL cholesterol levels by up to 60%, and it also has some beneficial effects on triglycerides and HDL cholesterol levels [1]. However, it has been associated with some side effects, including muscle pain, liver damage, and an increased risk of diabetes [2].

Crestor, also known as rosuvastatin, was approved by the FDA in 2003 and is a newer drug compared to Lipitor. It is only available in brand-name form and is typically taken once a day. Crestor has been shown to be more effective than Lipitor in reducing LDL cholesterol levels, with some studies showing reductions of up to 63% [3]. It also has some beneficial effects on triglycerides and HDL cholesterol levels. However, like Lipitor, it has been associated with some side effects, including muscle pain, liver damage, and an increased risk of diabetes [4].

In conclusion, both Lipitor and Crestor are effective drugs for reducing high cholesterol levels in the body. However, Crestor may be more effective in reducing LDL cholesterol levels compared to Lipitor. Ultimately, the choice between the two drugs will depend on a variety of factors, including the individual's medical history, the severity of their high cholesterol, and any other medications they may be taking. It is important to consult with a healthcare provider before starting any new medication.

Sources:
[1] https://www.medicalnewstoday.com/articles/drugs-lipitor-vs-crestor
[2] https://www.singlecare.com/blog/crestor-vs-lipitor/
[3] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[4] https://www.medicalnewstoday.com/articles/drugs-lipitor-vs-crestor