Lipitor, also known as atorvastatin, is a medication used to lower cholesterol levels in the blood. According to Drug Patent Watch [1], Lipitor was first approved by the FDA in 1996 and has been widely used since then. The effectiveness of Lipitor over time has been studied extensively, with research showing that it is effective in reducing cholesterol levels in the long term.

A study published in the Journal of the American College of Cardiology [2] analyzed the long-term effectiveness of atorvastatin in reducing cardiovascular events in patients with type 2 diabetes. The study followed patients for up to 9 years and found that atorvastatin was effective in reducing the risk of cardiovascular events, such as heart attack and stroke, over the long term.

Another study published in the Journal of Clinical Lipidology [3] evaluated the effectiveness of atorvastatin in reducing LDL cholesterol levels over a period of 12 months. The study found that atorvastatin was highly effective in reducing LDL cholesterol levels, with the greatest reduction occurring in the first 4 weeks of treatment.

Overall, the available research suggests that Lipitor is an effective medication for reducing cholesterol levels and reducing the risk of cardiovascular events over the long term. However, it is important to note that the effectiveness of Lipitor may vary depending on individual factors such as age, gender, and overall health status. As with any medication, it is important to consult with a healthcare provider to determine if Lipitor is an appropriate treatment option for you.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859299/
[3] https://pubmed.ncbi.nlm.nih.gov/25760954/