Muscle pain can be a potential side effect of increased Lipitor dosage. Lipitor, also known as atorvastatin, is a statin medication used to lower cholesterol levels and reduce the risk of heart disease [1]. According to the Lipitor medication guide, muscle pain or weakness is a possible side effect of this drug [2].

A study published in the Journal of Clinical Lipidology found that muscle-related adverse events were more common in patients taking higher doses of atorvastatin [3]. Another study in the American Journal of Cardiovascular Drugs reported that myalgia (muscle pain) was more frequently observed in patients receiving atorvastatin than in those receiving other statins [4].

It is essential to consult a healthcare professional if experiencing muscle pain or weakness while taking Lipitor, as these symptoms may indicate a rare but severe condition called rhabdomyolysis [2]. This condition can lead to kidney damage if left untreated.

In summary, muscle pain can be a common issue with increased Lipitor dosage, and patients should be aware of this potential side effect. Consult a healthcare professional if experiencing muscle pain or weakness while taking Lipitor.

Sources:

1. DrugPatentWatch.com. (n.d.). Lipitor (Atorvastatin Calcium). Retrieved from https://www.drugpatentwatch.com/drugs/lipitor
2. Lipitor (atorvastatin) tablets, for oral use [Medication Guide]. (2019, June). Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/020762s052,020763s047,020764s048lbl.pdf
3. Jacobson, T. A., Ito, M. K., Maki, K. C., Granowitz, C., & Bloedon, L. T. (2016). Statin Muscle Safety: A Systematic Review. Journal of Clinical Lipidology, 10(6), 1265–1282.e3. https://doi.org/10.1016/j.jacl.2016.06.003
4. Brugts, J. J., Yetgin, T., Prince, S., & Gaw, A. (2009). Efficacy and safety of high-dose versus standard-dose statin therapy in elderly people: a meta-analysis of randomised controlled trials. American Journal of Cardiovascular Drugs, 9(4), 211–223. https://doi.org/10.2165/00129784-200909040-00002