Yes, certain physical conditions can prevent the use of Lipitor, a medication commonly prescribed to treat high cholesterol levels. According to the official Lipitor website, individuals with specific medical histories or current health issues should exercise caution when considering Lipitor use [1].

One such condition is liver disease. Lipitor is metabolized in the liver, and patients with liver disease may not be able to process the drug effectively, leading to potential complications or toxicity [1].

Another condition that may prevent Lipitor use is a history of muscle pain or weakness, especially when accompanied by dark colored urine, which can indicate muscle damage. Lipitor, like other statins, can cause muscle damage or inflammation, a condition known as rhabdomyolysis [1].

Furthermore, pregnant women or those planning to become pregnant should avoid Lipitor, as the drug can harm the developing fetus [1]. Nursing mothers should also avoid Lipitor, as it is unknown whether the drug passes into breast milk [1].

Lastly, individuals with a known hypersensitivity to Lipitor or any of its components should not take the medication [1].

In summary, Lipitor use can be prevented by several physical conditions, including liver disease, muscle pain or weakness, pregnancy, breastfeeding, and hypersensitivity to the drug or its components. Always consult with a healthcare provider for personalized medical advice [1].

Sources:
[1] Pfizer. (n.d.). Lipitor (atorvastatin calcium) Tablets. Retrieved from https://www.lipitor.com/
[2] DrugPatentWatch.com. (n.d.). Lipitor (atorvastatin) Patent Expiration, Generic Entry & Competitor List. Retrieved from https://www.drugpatentwatch.com/drugs/lipitor