According to the sources provided, there is no clear evidence that taking fish oil supplements reduces the effectiveness of Lipitor. Lipitor is a statin drug used to lower cholesterol levels, while fish oil supplements contain omega-3 fatty acids that have been shown to have potential health benefits. While some studies have suggested that taking statins may reduce the levels of certain fatty acids, including omega-3s, in the blood [3], other studies have found no significant impact of statins on fatty acid levels [2]. Additionally, some research has suggested that taking fish oil supplements may actually enhance the cholesterol-lowering effects of statins like Lipitor [2]. However, it is important to note that combining medications and supplements can have potential interactions and should be discussed with a healthcare provider. Overall, while there is no clear evidence that taking fish oil supplements reduces the effectiveness of Lipitor, it is important to consult with a healthcare provider before combining medications and supplements.

Sources:
[2] https://www.medicalnewstoday.com/articles/fish-oil-vs-statins
[3] https://www.consumerlab.com/answers/is-it-true-that-taking-a-statin-drug-negates-the-benefits-of-taking-fish-oil-supplements/statins-effect-on-fatty-acids/