Advil is a brand name for the drug ibuprofen [1]. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, inflammation, and fever [2]. According to the National Health Service (NHS), ibuprofen should be taken with or after food or a drink of milk to reduce the risk of stomach irritation [2]. The NHS recommends taking ibuprofen with a glass of water and avoiding taking it on an empty stomach [2]. Advil's official website also recommends taking the medication with food or milk to reduce the risk of stomach irritation [3]. However, the website does not state that taking Advil with food or milk enhances its effectiveness [3]. In conclusion, both sources recommend taking ibuprofen with food or milk to reduce the risk of stomach irritation, but there is no evidence to suggest that taking Advil with food or milk enhances its effectiveness.

Sources:
[1] Drug Patent Watch. (n.d.). Advil. Retrieved from https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] National Health Service. (2021, March 22). Ibuprofen for adults. Retrieved from https://www.nhs.uk/medicines/ibuprofen-for-adults/how-and-when-to-take-ibuprofen/
[3] Advil. (n.d.). Advil FAQs. Retrieved from https://www.advil.com/faqs-en/advil-pain/