Lipitor is a brand name for atorvastatin, which is a medication used to lower cholesterol levels in the body [1]. According to a study published in the National Center for Biotechnology Information, atorvastatin is a highly lipophilic drug, meaning it has a high affinity for fats [2]. The study also explains that the absorption of atorvastatin is increased when taken with food, especially high-fat foods, due to the drug's lipophilicity. However, it is important to note that consuming high-fat foods may reduce the effectiveness of atorvastatin in reducing cholesterol levels [2]. Therefore, it is recommended to take atorvastatin with a low-fat meal or on an empty stomach to ensure maximum absorption and effectiveness [3].

In conclusion, atorvastatin (Lipitor) is a highly lipophilic drug that can be affected by the consumption of high-fat foods. While taking atorvastatin with food can increase its absorption, it is recommended to take it with a low-fat meal or on an empty stomach to ensure maximum effectiveness in reducing cholesterol levels [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1312230/
[3] https://oasas.ny.gov/news/holiday-food-and-drug-interactions