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Is weight change a side effect of advil in depression?

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Weight change is not explicitly listed as a side effect of Advil (ibuprofen) in the context of depression. Advil is a non-prescription, non-steroidal anti-inflammatory drug (NSAID) primarily used to treat pain, fever, and inflammation [1]. It is not typically used as a primary treatment for depression.

However, it's important to note that certain medications used to treat depression, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), can cause changes in weight as a side effect [2]. If a person is experiencing weight change while taking Advil and an antidepressant, it may be difficult to determine whether Advil or the antidepressant is causing the weight change.

In any case, if a person experiences significant weight change or any other unexpected symptoms while taking Advil or any other medication, they should consult with their healthcare provider.


1. [](
2. Mayo Clinic. (2021). Depression (major depressive disorder): Symptoms and causes. Retrieved from [](

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