According to the sources provided, there is a potential interaction between garlic and atorvastatin (Lipitor). Garlic may decrease the effectiveness of atorvastatin by reducing its absorption in the body. One study found that taking garlic supplements reduced the plasma concentration of atorvastatin by 20% [2]. However, the clinical significance of this interaction is not yet clear, and more research is needed to determine the extent of the interaction and its potential impact on patient outcomes [2].

It is important to note that the interaction between garlic and atorvastatin is not well-established, and more research is needed to fully understand the effects of this combination. Patients taking atorvastatin should talk to their healthcare provider before taking garlic supplements or making any changes to their medication regimen [3].

In conclusion, while there is some evidence to suggest that garlic may reduce the effectiveness of atorvastatin, the clinical significance of this interaction is not yet clear. Patients taking atorvastatin should talk to their healthcare provider before taking garlic supplements or making any changes to their medication regimen.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997463/
[3] https://www.drugs.com/drug-interactions/atorvastatin-with-garlic-276-0-1160-0.html