There is no known interaction between guacamole and Lipitor, according to the sources provided. Lipitor is a brand name for atorvastatin, a medication used to lower cholesterol levels in the blood [1]. While there are some food and medication interactions that can affect the effectiveness of Lipitor, such as grapefruit juice and some antibiotics, there is no mention of guacamole in the sources provided [2][3]. However, it is always important to consult with a healthcare provider or pharmacist about any potential food or medication interactions before starting a new medication or changing your diet.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.aarp.org/health/drugs-supplements/info-2022/food-medication-interaction.html
[3] https://www.statnews.com/2016/11/03/medications-food-drug-interactions/